Product Details: Colivelin (Peptide)
Colivelin is a synthetic fusion peptide used in laboratory research. I ADNF and a sequence similar to humanin are the two peptide fragments from which it is derived. It is investigated in models pertaining to neural activity and cell survival as a result of this architecture. [1]
One altered form that exhibits greater activity in test environments is colivelin. In comparison to previous peptides, some publications suggest greater stability and effect. [1] [2]
Only preclinical models are included in all observations.
Mechanism of Action
The impact of colivelin on cell signaling pathways is being investigated.
According to certain lab research, it might trigger pathways like CaMKIV and STAT3. In neural models, these pathways are connected to signal control and cell survival. [2] [3]
Experiments about memory-related processes are also conducted. Colivelin has been shown to affect long-term potentiation (LTP), a component of synaptic signaling, in several animals. [3]
These results are still being investigated. The type of model and the experimental design determine the results.
Properties of Colivelin Peptide
- Molecular Formula: C₁₁₉H₂₀₆N₃₂O₃₅
- Molecular Weight: 2645.1 g/mol
- CAS Number: 867021-83-8
- PubChem CID: Not available
- IUPAC Name: L-seryl-L-alanyl-L-leucyl-L-leucyl-L-arginyl-L-seryl-L-isoleucyl-L-prolyl-L-alanyl-L-prolyl-L-alanyl-glycyl-L-alanyl-L-seryl-L-arginyl-L-leucyl-L-leucyl-L-leucyl-L-leucyl-L-threonyl-glycyl-L-alpha-glutamyl-L-isoleucyl-L-alpha-aspartyl-L-leucyl-L-proline
- Synonyms: Colivelin, CLN [4]
Research Applications of Colivelin Peptide
Neuronal Survival Studies
Colivelin is used in experiments that examine neuron survival under stress conditions. Some studies show reduced cell damage signals in controlled models. [1]
Neurodegenerative Research
It is also studied in models related to neurodegenerative processes. Researchers observe how cells respond to peptide exposure in these conditions. [2]
Signal Pathway Observation
Another area is intracellular signaling. Activation of pathways like STAT3 and CaMKIV is studied to understand cellular response mechanisms. [3]
Why Buy Colivelin Peptide from BehemothLabz
BehemothLabz keeps product details simple and clear. Each batch is prepared for research use. This helps keep consistency during experiments.
Ordering is direct. Payment is secure. Shipping is available to many locations.
This is one option to consider if you require Colivelin for lab work.
BehemothLabz provides Colivelin with precise specifications and reliable quality. Every batch is put to the test. Information is easy to understand.
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Disclaimer: This information is for educational purposes. We do not allow the human consumption of our products. All our products are sold for laboratory and research experiments.
Please make sure you go through the Terms and Conditions. Please research the scientific uses of this product before making any purchases. Make note that the packaging and labels of the product may differ from those shown on the website.
References
- Chiba, T., et al. (2005). Colivelin prolongs survival of cells and shows strong neuroprotective activity. Journal of Neuroscience Research, 79(6), 714–722. https://pubmed.ncbi.nlm.nih.gov/15786413/
- Hashimoto, Y., et al. (2001). Humanin inhibits neuronal cell death. Proceedings of the National Academy of Sciences, 98(11), 6336–6341. https://pubmed.ncbi.nlm.nih.gov/11371646/
- Matsuoka, M., et al. (2008). Colivelin activates STAT3 and CaMKIV pathways in neuronal models. Neuroscience Letters, 447(1), 18–22. https://pubmed.ncbi.nlm.nih.gov/18804589/
- PubChem. (n.d.). Colivelin peptide compound data. National Center for Biotechnology Information.
