Phenibut FAA Capsules (Free Amino Acid)
Phenibut FAA Capsule (Free Amino Acid) is the derivative form of Phenibut with an extra phenyl ring in its structure. Phenibut itself is a synthetic analogue of the neurotransmitter gamma-aminobutyric acid (GABA), where the addition of a phenyl group allows it to cross biological membranes more efficiently in experimental models.
In research settings, Phenibut has been studied for its interaction with GABA_B receptors and related signaling pathways. This contributes to investigations in neurochemical modulation and receptor activity.
Mechanism of Action of Phenibut FAA Capsules
The mechanism of action of Phenibut FAA Capsules may involve its interaction with GABA receptors (Gamma-Aminobutyric acid). In experimental research, Phenibut has been shown to primarily act on GABA_B receptors, where it may influence inhibitory neurotransmission and neuronal signaling pathways.
Some studies also suggest that Phenibut may interact with voltage-dependent calcium channels, which are involved in regulating neurotransmitter release in neural systems. These interactions are being investigated in research settings to better understand their role in neurochemical signaling and synaptic activity.
Properties of Phenibut FAA Capsules (Free Amino Acid)
- Chemical Formula: C10H13NO2
- Synonym: 4-Amino-3-phenylbutanoic acid, Phenibut, Fenibut, Fenigam, phenygam, phenigamma, PhGaba.
- IUPAC-Name: 4-Amino-3-phenylbutanoic acid
- Molar Mass: 179.22 g/mol
- CAS Number: 1078-21-3
- PubChem CID: 14113
- Shelf Life: 36 months
Research Findings on Phenibut FAA Capsules
Research suggests how phenibut interacts with voltage-dependent calcium channels in neural systems. In experimental studies using animal brain tissue, phenibut was found to bind to the α2-δ subunit of these calcium channels, which are important for regulating neurotransmitter release and neuronal signaling. This interaction was observed to play a significant role in modulating neural activity, suggesting that phenibut may influence synaptic transmission through mechanisms beyond GABA receptor activity.
Another research has focused on phenibut’s activity at GABA_B receptors in experimental neural models. Studies using isolated spinal cord and neuronal preparations have shown that phenibut can act as a GABA_B receptor agonist. This leads to changes in neuronal excitability and suppression of certain signaling activities. This interaction has been linked to alterations in synaptic transmission and neuronal response patterns. This makes it a subject of interest in research related to inhibitory neurotransmission and receptor-mediated signaling pathways.
Note: Phenibut FAA Capsules are not approved by the FDA for any medical use. It does not qualify as a dietary ingredient and is available for research purposes only.
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Reference Links
PubChem. (2026). Phenibut. Nih.gov; PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Phenibut
Zvejniece, L., Vavers, E., Svalbe, B., Veinberg, G., Rizhanova, K., Liepins, V., Kalvinsh, I., & Dambrova, M. (2015). R-phenibut binds to the α2–δ subunit of voltage-dependent calcium channels and exerts gabapentin-like anti-nociceptive effects. Pharmacology Biochemistry and Behavior, 137, 23–29. https://doi.org/10.1016/j.pbb.2015.07.014
Abramets, I. I., & Komissarov, I. V. (1985). Effect of fenibut on the GABA B receptors of the spinal motor neurons. Biulleten’ Eksperimental’noi Biologii i Meditsiny, 99(6), 698–700. https://pubmed.ncbi.nlm.nih.gov/2861865/
