Product Details
Tesamorelin is a synthetic peptide analog composed of amino acid residues arranged to mimic specific segments of endogenous regulatory peptides. It is structurally designed to interact with receptor systems associated with growth hormone-releasing pathways. Within controlled research environments, Tesamorelin is examined for its involvement in peptide-receptor interactions and intracellular signaling mechanisms related to endocrine regulation.
Mechanism of Action
Tesamorelin functions as an analog of growth hormone-releasing factor (GHRF) and is studied for its interaction with GHRF receptors located on pituitary-associated cells. Upon receptor binding, it may initiate intracellular signaling cascades involving cyclic adenosine monophosphate (cAMP) pathways.
This receptor-mediated activation is associated with downstream signaling events that influence the synthesis and release of growth hormone at the molecular level. Subsequent signaling pathways include modulation of insulin-like growth factor (IGF-1) expression and regulation of metabolic enzyme activity through phosphorylation-dependent mechanisms.
Additionally, Tesamorelin has been explored for its interaction with pathways involved in lipid metabolism, including those associated with lipolytic signaling and fatty acid mobilization at the cellular level. These processes are studied in relation to receptor activation and downstream biochemical responses rather than outcome-based effects.
Chemical Properties of Tesamorelin
| Property | Value |
| Product Name | Tesamorelin |
| Chemical Classification | Synthetic peptide analog |
| Molecular Formula | C221H366N72O67S |
| Molecular Weight | 528.67 g·mol⁻¹ |
| CAS Number | 218949-48-5 |
| Structure Type | Peptide-based GHRF analog |
| Synonyms | MK-677, MK-0677, L-163,191, Oratrope |
Research Applications
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GHRF Receptor Binding Studies
Tesamorelin is utilized in research examining ligand-receptor interactions specific to growth hormone-releasing factor receptors. These studies focus on binding affinity, receptor activation, and downstream signaling initiation.
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cAMP-Mediated Signaling Pathways
The compound is investigated for its role in modulating intracellular cAMP levels following receptor activation. Research explores how this signaling pathway influences phosphorylation cascades and enzyme regulation.
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Endocrine Axis Signaling Analysis
Tesamorelin is studied for its involvement in pathways associated with the hypothalamic-pituitary signaling axis. This includes evaluating molecular interactions that regulate peptide-mediated signaling within endocrine systems.
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Lipid Metabolism Pathway Research
Research explores how Tesamorelin interacts with biochemical pathways linked to lipid metabolism, including signaling mechanisms associated with fatty acid mobilization and enzymatic regulation at the cellular level.
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IGF-1 Pathway Exploration
The peptide is also examined for its downstream influence on insulin-like growth factor signaling pathways. Studies focus on transcriptional and post-translational regulation associated with these molecular processes.
Why Choose BehemothLabz to Buy Tesamorelin for Research
BehemothLabz provides research-grade Tesamorelin manufactured under controlled laboratory conditions with strict quality assurance protocols. Each batch undergoes analytical verification to ensure consistency in molecular composition and purity.
Comprehensive documentation, including laboratory testing reports and sourcing transparency, supports reproducibility in experimental settings. BehemothLabz maintains a compliance-focused approach, supplying compounds intended strictly for laboratory-based investigation and analytical research
Disclaimer
Tesamorelin is intended strictly for laboratory research and analytical purposes only. It is not intended for use in diagnostic procedures, therapeutic applications, or in vivo studies of any kind.Any references to biochemical pathways, receptor interactions, or enzymatic processes are provided solely for informational and research-context purposes. This compound must be handled exclusively by qualified professionals in controlled laboratory environments in accordance with applicable regulations and safety guidelines.
Improper handling or use outside of controlled research settings is strictly prohibited.
References
- Fourman, L. T., Billingsley, J. M., Agyapong, G., Ho Sui, S. J., Feldpausch, M. N., Purdy, J., Zheng, I., Pan, C. S., Corey, K. E., Torriani, M., Kleiner, D. E., Hadigan, C. M., Stanley, T. L., Chung, R. T., & Grinspoon, S. K. (2020). Effects of tesamorelin on hepatic transcriptomic signatures in HIV-associated NAFLD. JCI insight, 5(16), e140134. https://doi.org/10.1172/jci.insight.140134
- Mangili, A., Falutz, J., Mamputu, J. C., Stepanians, M., & Hayward, B. (2015). Predictors of Treatment Response to Tesamorelin, a Growth Hormone-Releasing Factor Analog, in HIV-Infected Patients with Excess Abdominal Fat. PloS one, 10(10), e0140358. https://doi.org/10.1371/journal.pone.0140358
